Juergen KROYMANN

Function, Ecology and Evolution of Plant Specialized Metabolism in the Brassicales; Plant-Insect Interactions; Host Plant Defenses and Insect Counteradaptations; Plant Adaptation to Extreme Environments; Function and Evolution of Multigene Families

• 2012 – 2022:  Head of the GEE team
• since 2009:  Senior scientist, CNRS
• 2007:  Habilitation in Life Sciences, University Paris-South
• 2007:  Invited professor, University Paris-South
• 1998 – 2008:  Post-doc and Group leader, Max Planck Institute for Chemical Ecology
• 1993 – 1997:  PhD thesis. University of Giessen
• 1993:  Biology diploma, University of Giessen

• Host Plant Adaptation in Plutellid Moths (ANR/DFG, 2021-2025)
• Evolutionary and Functional Genomics of Modified Indole Glucosinolate Biosynthesis (ANR, 2011 – 2015)
• Expressed Sequence Tags of Toxic Algae (European Union, 2005 – 2007)
• Quantification of Insect Resistance in Arabidopsis Ecotypes (German Federal Ministry for Science and Education, 2004 – 2006)
• Comparative Evolutionary Analysis of Methylthioalkylmalate Synthase Genes and Enzymes in the Capparales (DFG, 2004 – 2009)
• Mapping of QTLs for Heterosis and Identification of the Responsible Gene Loci in Arabidopsis (DFG, 2004 – 2005)

Peer-reviewed articles

Pormetter L, Pfalz M, Kagho MD, Klahn P, Vogel H, Kroymann J, Wittstock U (2025). Glucosinolate diversity in seven field-collected Brassicaceae species. PLOS ONE 20: e0336172.

Pfalz M, Naadja SE, Shykoff J, Kroymann J (2025). Ectopic gene conversion causing quantitative trait loci. Mol. Biol. Evol. 42, 1-20.

Mukhaimar M, Pfalz M, Shykoff J, Kroymann J (2024). Natural genetic variation and negative density effects in plant-nematode interactions. Plant-Environ. Interact. 5: e10133.

Okamura Y, Sato A, Kawaguchi L, Nagano AJ, Murakami M, Vogel H, Kroymann J (2022). Microevolution of Pieris butterfly genes involved in host-plant adaptation along a host-plant community cline. Mol. Ecol. 31, 3083-3097.

Spielmann J, Hassan A, Scheepers M, Weber M, Nitsche S, Carnol M, Bosman B, Kroymann J, Motte P, Clemens S, Hanikenne M (2020). The two copies of the zinc and cadmium ZIP6 transporter of Arabidopsis halleri have distinct effects on cadmium tolerance and fertility. Plant Cell Environ. 43, 2143-2157.

Ouassou M, Mukhaimar M, El Amrani A, Kroymann J, Chauveau O (2019) Biosynthèse des glucosinolates indoliques et rôle écologique de leurs modifications secondaires. C. R. Biologies C. R. Biologies 342, 58-80.

Heidel-Fischer HM, Kirsch R, Reichelt M, Ahn SJ, Wielsch N, Baxter SW, Heckel DG, Vogel H, Kroymann J (2019) An insect counteradaptation against host plant defenses evolved through concerted neofunctionalization. Mol. Biol. Evol. 36, 930-941.

Pfalz M, Mukhaimar M, Perreau F, Kirk J, Hansen CIC, Olsen CE, Agerbirk N, Kroymann J (2016) Methyl transfer in glucosinolate biosynthesis mediated by indole glucosinolate O-methyltransferase 5. Plant Physiol. 172, 2190-2203.

de Marchi R, Sorel M, Mooney B, Fudal I, Goslin K, Kwa?niewska K, Ryan PT, Pfalz M, Kroymann J, Pollmann S, Feechan A, Wellmer F, Rivas S, Graciet E (2016) The ubiquitin-dependent N-end rule pathway regulates pathogen responses in plants. Scientific Reports 6: 26020.

Pentzold S, Zagrobelny M, Bjarnholt N, Kroymann J, Vogel H, Olsen CE, Møller BL, Bak S (2015) Metabolism, excretion and avoidance of plant cyanogenic glucosides in insects with different feeding specialisations. Insect Biochem. Molec., 66, 119-128.

Hanikenne M, Kroymann J, Trampczynska A, Bernal M, Motte P, Clemens S, Krämer U (2013) Hard selective sweep and ectopic gene conversion in a gene cluster affording environmental adaptation. PLOS Genetics 9: e1003707.

Jaeckisch N, Yang I, Wohlrab S, Glöckner G, Kroymann J, Vogel H, Cembella A, John U (2011) Comparative genomic and transcriptomics characterization of the toxigenic marine dinoflagellate Alexandrium ostenfeldii. PLOS ONE 6: e28012.

Kroymann J (2011) Natural diversity and adaptation in plant secondary metabolism. Curr. Opin. Plant Biol. 14, 246-251.

Pfalz M, Mikkelsen MD, Bednarek P, Olsen CE, Halkier BA, Kroymann J (2011) Metabolic engineering in Nicotiana benthamiana reveals key enzyme functions in Arabidopsis indole glucosinolate modification. Plant Cell 23, 716-729.

Pfalz M, Vogel H, Kroymann J (2009) The gene controlling the Indole Glucosinolate Modifier 1 QTL alters indole glucosinolate structures and aphid resistance in Arabidopsis. Plant Cell 21, 985-999.

Benderoth M, Pfalz M, Kroymann J (2009) Methylthioalkylmalate synthases: Genetics, ecology and evolution. Phytochem. Rev. 8, 255-268.

Hanikenne M, Talke IN, Haydon MJ, Lanz C, Nolte A, Motte P, Kroymann J, Weigel D, Krämer U (2008) Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4. Nature 453, 391-395.

Oyama RK, Clauss MJ, Formanová N, Kroymann J, Schmid KJ, Vogel H, Weniger K, Windsor AJ, Mitchell-Olds T (2008) The shrunken genome of Arabidopsis thaliana. Plant Syst. Evol. 273, 257-271.

Böttcher C, Centeno D, Freitag J, Höfgen R, Köhl K, Kopka J, Kroymann J, Matros A, Mock HP, Neumann S, Pfalz M, von Roepenack-Lahaye E, Schauer N, Trenkamp S, Zubriggen M, Fernie AR (2008) Teaching (and learning from) metabolomics: The 2006 PlantMetaNet ETNA metabolomics research school. Physiol. Plant. 132, 136-149.

Vogel H, Kroymann J, Mitchell-Olds T (2007) Different transcript patterns in response to specialist and generalist herbivores in the wild Arabidopsis relative Boechera divaricarpa. PLOS ONE 2, e1081.

Pfalz M, Vogel H, Mitchell-Olds T, Kroymann J (2007) Mapping of QTL for resistance against the crucifer specialist insect herbivore Pieris brassicae in a new Arabidopsis recombinant inbred line population, Da(1)-12 × Ei-2. PLOS ONE 2, e578.

Benderoth M, Textor S, Windsor AJ, Mitchell-Olds T, Gershenzon J, Kroymann J (2006) Positive selection driving diversification in plant secondary metabolism. Proc. Natl. Acad. Sci. USA 103, 9118-9123.

Heidel AJ, Clauss M, Kroymann J, Savolainen O, Mitchell-Olds T (2006) Natural variation in MAM within and between populations of Arabidopsis lyrata determines glucosinolate phenotype. Genetics 173, 1629-1636.

Windsor AJ, Schranz ME, Formanová N, Gebauer-Jung S, Bishop JG, Schnabelrauch S, Kroymann J, Mitchell-Olds T (2006) Partial shotgun sequencing of the Boechera stricta genome reveals extensive microsynteny and promoter conservation with Arabidopsis thaliana. Plant Physiol. 140, 1169-1181.

Knight C, Vogel H, Kroymann J, Shumate A, Witsenboer H, Mitchell-Olds T (2006) Expression profiling and local adaptation of Boechera holboellii populations for water use efficiency across a naturally occurring water stress gradient. Mol. Ecol. 15, 1229-1237.

Voigt K, Cozijnsen AJ, Kroymann J, Pöggeler S, Howlett BJ (2005) Phylogenetic relationships between members of the crucifer pathogenic Leptosphaeria maculans species complex as shown by mating type (MAT1-2), actin and b-tubulin sequences. Mol. Phylo. Evol. 37, 541-557.

Kroymann J, Mitchell-Olds T (2005) Epistasis and balanced polymorphism influencing complex trait variation. Nature 435, 95-98.

Kliebenstein DJ, Kroymann J, Mitchell-Olds T (2005) The glucosinolate-myrosinase system in an ecological and evolutionary context. Curr. Opin. Plant Biol. 8, 264-271.

Windsor AJ, Reichelt M, Figuth A, Svatoš A, Kroymann J, Kliebenstein DJ, Gershenzon J, Mitchell-Olds T (2005) Geographic and evolutionary diversification of glucosinolates among near relatives of Arabidopsis thaliana (Brassicaceae). Phytochemistry 66, 1321-1333.

Textor S, Bartram S, Kroymann J, Falk KL, Hick A, Pickett JA, Gershenzon J (2004) Biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana: Recombinant expression and characterization of methylthioalkylmalate synthase, the condensing enzyme of the chain elongation cycle. Planta 218, 1026-1035.

Kroymann J, Donnerhacke S, Schnabelrauch D, Mitchell-Olds T (2003) Evolutionary dynamics of an Arabidopsis insect resistance quantitative trait locus. Proc. Natl. Acad. Sci. USA 100, 14587-14592.

Ratzka A, Vogel H, Kliebenstein DJ, Mitchell-Olds T, Kroymann J (2002) Disarming the mustard oil bomb. Proc. Natl. Acad. Sci. USA 99, 11223-11228.

Haubold B, Kroymann J, Ratzka A, Mitchell-Olds T, Wiehe T (2002) Recombination and gene conversion in a 170 kb genomic region of Arabidopsis thaliana. Genetics 161, 1269-1278.

Koch MA, Weisshaar B, Kroymann J, Haubold B, Mitchell-Olds T (2001) Comparative genomics and regulatory evolution: conservation and function of the Chs and Apetala3 promoters. Mol. Biol. Evol. 18, 1882-1891.

Kroymann J, Textor S, Tokuhisa JG, Falk KL, Bartram S, Gershenzon J, Mitchell-Olds T (2001) A gene controlling variation in Arabidopsis thaliana glucosinolate composition is part of the methionine chain elongation pathway. Plant Physiol. 127, 1077-1088.

Kliebenstein DJ, Kroymann J, Brown PD, Figuth A, Pedersen D, Gershenzon J, Mitchell-Olds T (2001) Genetic control of natural variation in Arabidopsis thaliana glucosinolate accumulation. Plant Physiol. 126, 811-825.

Campos de Quiros H, Magrath HCR, McCallum D, Kroymann J, Schnabelrauch D, Mitchell-Olds T, Mithen R (2000) Quantitative trait loci and the biochemical genetics of glucosinolate biosynthesis in Arabidopsis thaliana. Theor. Appl. Genet. 101, 429-437.

Stotz HU, Pittendrigh B, Kroymann J, Weniger K, Fritsche J, Bauke A, Mitchell-Olds T (2000) Induced plant defense expression against chewing insects: ethylene signaling reduces resistance of Arabidopsis against egyptian cotton worm but not diamondback moth. Plant Physiol. 124, 999-1009.

Stotz HU, Kroymann J, Mitchell-Olds T (1999) Plant-insect interactions. Curr. Opin. Plant Biol. 2, 268-272.

Kroymann J, Zetsche K (1998) The mitochondrial genome of Chlorogonium elongatum inferred from the complete sequence. J. Mol. Evol. 47, 431-440.

Kroymann J, Zetsche K (1997) The apocytochrome-b gene in Chlorogonium elongatum: An intronic GIY-YIG ORF in green algal mitochondria. Curr. Genet. 31, 514-518.

Kroymann J, Schneider W, Zetsche K (1995) Opposite regulation of the copy number and the expression of plastid and mitochondrial genes by light and acetate in the green flagellate Chlorogonium. Plant Physiol. 108, 1641-1646.

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Books, book chapters, etc.

Pormetter L, Pfalz M, Kroymann J, Vogel H, Wittstock U (2024). Host plant adaptation in Plutellid moths – Do glucosinolate sulfatase specificities match host plant glucosinolate spectra? Symposium on Plant-Insect Relationships 2025, Bielefeld.

Ouassou M, Pfalz M, Kroymann J (2017). Function and evolution of indole glucosinolate modification pathways. In: Hanschen FS, Schreiner M, Wiesner-Reinhold M (eds.) Glucosinolate Summit. Proceedings of the 4^th International Glucosinolate Conference 2017, IGZ Leibniz Institute of Vegetable and Ornamental Crops (ISBN: 978-3-9818967-9-4), p 26.

Pfalz M, Mukhaimar M, Paupière M, Shehadi M, Ouassou M, Kroymann J (2014). Indole glucosinolate modification in Arabidopsis. In: G. Bonnema and R. Verkerk (eds.) Glucosinolates & beyond. Proceedings of the 3^rd International Glucosinolate Conference 2014, Wageningen University, The Netherlands (ISBN: 978-94-6257-382-6), p 28.

Hanikenne M, Talke IN, Hamilton C, Lanz C, Kroymann J, Motté P, Weigel D, Krämer U (2008). Promoter activation determines high transcript levels of metal transporter genes in the Zn hyperaccumulator Arabidopsis halleri. Rank Prize Funds Symposium: “Transport of Micronutrients in Animals and Plants”.

Krämer U, Talke IN, Hanikenne M, Haydon M, Lanz C, Nolte A, Motté P, Kroymann J, Weigel D (2008). Evolution of metal hyperaccumulation through cis-regulatory changes and gene copy number expansion of a gene encoding a P1B-type Zn/Cd-ATPase. Trace element metabolism: From model organisms to humans.

Vogel H, Kroymann J, Mithöfer A, Boland W, Heckel D (2007). Can insects manipulate plant defenses? J. Ins. Sci. 7.

Hanikenne M, Talke IN, Kroymann J, Hamilton C, Motté P, Lanz C, Krämer U (2007). Strongly enhanced promoter activities contribute to high transcript levels of metal transporter genes in the Zn/Cd hyperaccumulator A. helleri. XIV International Workshop on Plant Membrane Biology, Valencia, Spain.

Cembella A, John U, Medlin L, Valentin KU, Kooistra WHCF, Montressor M, Bowler C, Hayes PK, Glöckner G, Vogel H, Kroymann J (2006). Towards understanding toxin production and bloom formation of microalgae: Expressed sequence tags of toxic algae (ESTTAL), Marine Genomics International Conference 28, Sorrento, Italy.

Mitchell-Olds T, Kroymann J, Clauss M, Vogel H (2005). Öko-und Chemotypen der Ackerschmalwand (Arabidopsis thaliana) und ihrer Verwandten: Was waren und was sind die Antriebsfedern der Evolution ihrer Insektenresistenz. Jahrbuch der Max-Planck-Gesellschaft 2005.

Hanikenne M, Talke IN, Galante C, Kroymann J, Krämer U (2005). Study of metal regulation in Arabidopsis halleri, a model system to understand zinc homeostasis in plants. Gordon Research Conferences – Cell Biology of Metals. Lewiston, Maine, US.

Vogel H, Kroymann J, Ratzka A, Mitchell-Olds T (2004). Coping with glucosinolates: disarming the mustard oil bomb. Management of Diamondback Moth and other Crucifer Pests, p 159.

Kroymann J, Mitchell-Olds T (2004). Function and evolution of an Arabidopsis insect resistance QTL. In: Tikhonovich I, Lugtenberg B, Provorov N (eds.) Biology of Molecular Plant-Microbe Interactions, Vol. 4. International Society of Molecular Plant-Microbe Interactions, APS Press, pp 259-262.

Stotz HU, Kroymann J, Tobler M, Mitchell-Olds T (2000). Systematic genetic and molecular analysis of insect resistance in Arabidopsis. In: de Wit PJGM, Bisseling T, Stiekema WJ (eds.) Biology of Plant-Microbe Interactions, Vol. 2. International Society of Plant-Microbe Interactions, St. Paul, pp 373-373.

Kroymann J (1997). Das Mitochondriengenom der einzelligen Grünalge Chlorogonium elongatum – Neue Erkenntnisse zur Evolution der Mitochondriengenome in Chlamydomonadaceen. Dissertation, Universität Gießen. Tectum Verlag, Marburg.

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Vulgarisation

Kroymann J (2025). Conversion de gènes ectopiques à l’origine de la variation des charactère quantitatifs. Scoop.it – Life Sciences Université Paris-Saclay.

Kroymann J (2022). Adaptation locale chez les papillons Pieris. Scoop.it – Life Sciences Université Paris-Saclay.

Kroymann J (2019). La « néofonctionnalisation concertée » explique l’évolution d’une contre-adaptation de la Teigne de choux contre les défenses chimiques de ses plant hôtes. Scoop.it – Life Sciences Université Paris-Saclay.

Kroymann J, Heraudet V (2019). Focus Plateforme : Comprendre la variation génétique naturelle dans la défense d’Arabidopsis contre les espèces phytoparasites ! Scoop.it – Life Sciences Université Paris-Saclay.

Kroymann J (2009). Blattlaus-Alarm: Senföl-Glycoside schützen. Press release, Max Planck Society.

Kroymann J (2006). Neue Sprengkraft für die Senfölbombe. Press release, Max Planck Society.

Kroymann J (2002). Die Entschärfung der Senfölbombe. Press release, Max Planck Society.